Clinical-laboratory characteristic and arterial blood pressure in children of under school and early school age with obesity

For the last 20 years obesity and overweight in childhood have become one of the most important healthcare problems for the vast majority of countries, including Russia. There is a data that obesity in early age correlates with the risk factors of chronic diseases in adultness, including diabetes, cardio-vascular diseases, arterial hypertension and many others. That is why the main goal of our survey was to compare clinical-laboratory parameters and lab based indicators and to explore the details of arterial blood pressure indicators of pre-school and younger school children with and without obesity in one region of Russia (Lipetsk Region). We have analyzed those parameters in 2 groups of children: first group consisted of 50 children with obesity, and second 50 children with normal body mass. For checking the differences between two groups we have used Students t-test or its counterpart for independent samples MannWhitney U-test in cases when the variances of the values were high. The results of survey have shown the high index of hereditary burden among children with obesity, more birth weight of those ones, higher levels of glucose, cholesterol, and low density triglicerids andindex atherogenicity. The measurements of arterial blood pressure (systolic and diastolic) three times per day every day during a week showed significant increasing from mornings to evenings and from the beginning to the end of the week. The highest number of significant coefficients of correlation has been revealed between body mass of the children with obesity and arterial blood pressure (systolic and diastolic) during the day.