Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient

2020365 citationsJournal Articlegold Open Access

Authors

Jing Sun · First Affiliated Hospital of Guangzhou Medical University

Airu Zhu · First Affiliated Hospital of Guangzhou Medical University

Heying Li · Chinese Academy of Sciences

Kui Zheng

Zhen Zhuang · First Affiliated Hospital of Guangzhou Medical University

Chen Zhao · First Affiliated Hospital of Guangzhou Medical University

Yongxia Shi

Zhaoyong Zhang

Abstract

SARS-CoV-2 caused a major outbreak of severe pneumonia (COVID-19) in humans. Viral RNA was detected in multiple organs in COVID-19 patients. However, infectious SARS-CoV-2 was only isolated from respiratory specimens. Here, infectious SARS-CoV-2 was successfully isolated from urine of a COVID-19 patient. The virus isolated could infect new susceptible cells and was recognized by its' own patient sera. Appropriate precautions should be taken to avoid transmission from urine.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research COVID-19 Clinical Research Studies SARS-CoV-2 detection and testing

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Emerging Microbes & Infections

Volume 9, Issue 1, pp. 991-993

DOI: 10.1080/22221751.2020.1760144

Field-Weighted Citation Impact: 8.39