Reversal Effect of Dihydromyricetin on Multiple Drug Resistance in SGC7901/5-FU Cells

202013 citationsJournal Articlegold Open Access

Authors

Mingcai Wu · Wannan Medical College

Ming Jiang · Anhui Conch Design and Research Institute of Building Materials (China)

Ting Dong · Anhui University of Traditional Chinese Medicine

Lei Xu · Wannan Medical College

Jun Lv · Wannan Medical College

Mengya Xue · Wannan Medical College

Mengzhu Huang

Abstract

In brief, our study demonstrated that DMY effectively reversed multi-drug resistance occurring in SGC7901/5-FU cells cultured in vitro, and the potential mechanism was involved in the downregulation of the MDR1 expression.

Topics & Keywords

Medicinal plant effects and applications Biological Activity of Diterpenoids and Biflavonoids Inflammatory mediators and NSAID effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Asian Pacific Journal of Cancer Prevention

Volume 21, Issue 5, pp. 1269-1274

DOI: 10.31557/apjcp.2020.21.5.1269

Field-Weighted Citation Impact: 1.73