Identification of Key Genes of Human Advanced Diabetic Nephropathy Independent of Proteinuria by Transcriptome Analysis

20207 citationsJournal Articlehybrid Open Access

Authors

Fanghao Cai · Peking University

Shu‐Feng Zhou · Peking University

Yan Jia · Peking University

Weijian Yao · Peking University

Jicheng Lv · Peking University

Gang Liu · Peking University

Li Yang · Peking University

Abstract

Our study identified pathways including fibrosis, inflammation, lipid metabolism, and oxidative stress contributing to the progression of DN independent of proteinuria. These genes may serve as biomarkers and therapeutic targets.

Topics & Keywords

Chronic Kidney Disease and Diabetes Renal Diseases and Glomerulopathies Renal and Vascular Pathologies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BioMed Research International

Volume 2020, Issue 1, pp. 7283581-7283581

DOI: 10.1155/2020/7283581

Field-Weighted Citation Impact: 0.70