Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain

2020417 citationsletterhybrid Open Access

Authors

Michael Verret · Canadian Institutes of Health Research

François Lauzier · Canadian Institutes of Health Research

Ryan Zarychanski · Canadian Institutes of Health Research

Caroline Perron · Canadian Institutes of Health Research

Xavier Savard · Canadian Institutes of Health Research

Anne-Marie Pinard · Canadian Institutes of Health Research

Guillaume Leblanc

Abstract

No clinically significant analgesic effect for the perioperative use of gabapentinoids was observed. There was also no effect on the prevention of postoperative chronic pain and a greater risk of adverse events. These results do not support the routine use of pregabalin or gabapentin for the management of postoperative pain in adult patients.

Topics & Keywords

Anesthesia and Pain Management Pediatric Pain Management Techniques Pain Management and Opioid Use

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anesthesiology

Volume 133, Issue 2, pp. 265-279

DOI: 10.1097/aln.0000000000003428

Field-Weighted Citation Impact: 57.05