Differential effects of vagus nerve stimulation paradigms guide clinical development for Parkinson’s disease

202063 citationsJournal Articlegold Open Access

Authors

Ariana Q. Farrand · Medical University of South Carolina

Ryan Verner · LivaNova (United States)

Ryan M. McGuire · LivaNova (United States)

Kristi L. Helke · Medical University of South Carolina

Vanessa K. Hinson · Medical University of South Carolina

Heather A. Boger · Medical University of South Carolina

Abstract

These data indicate that higher stimulation frequencies provided the greatest attenuation of behavioral and pathological markers in this PD model, indicating therapeutic potential for these VNS paradigms.

Topics & Keywords

Vagus Nerve Stimulation Research EEG and Brain-Computer Interfaces Neurological disorders and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Brain stimulation

Volume 13, Issue 5, pp. 1323-1332

DOI: 10.1016/j.brs.2020.06.078

Field-Weighted Citation Impact: 3.27