Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder

202079 citationsJournal Articlehybrid Open Access

Authors

Sanne Kloosterboer · Erasmus MC

Brenda C. M. de Winter · Erasmus MC

Catrien G. Reichart · Leiden University Medical Center

Mirjam E. J. Kouijzer · GGz Breburg

Matthias M. J. de Kroon · Breda University of Applied Sciences

Emma van Daalen · Yulius

Wietske A. Ester ·

Abstract

Our results indicate a therapeutic window exists, which suggests that therapeutic drug monitoring of risperidone might increase safety and effectiveness in children and adolescents with ASD and behavioural problems.

Topics & Keywords

Attention Deficit Hyperactivity Disorder Pharmaceutical studies and practices Autism Spectrum Disorder Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Clinical Pharmacology

Volume 87, Issue 3, pp. 1069-1081

DOI: 10.1111/bcp.14465

Field-Weighted Citation Impact: 8.94