Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid

202014 citationsJournal Articlebronze Open Access

Authors

Kirstine Kirkegaard · Aarhus University Hospital

Yan Yan · Aarhus University

Boe Sandahl Sørensen · Aarhus University Hospital

Thorir Hardarson · Fertilitetscentrum

Charles Hanson · Sahlgrenska University Hospital

Hans Jakob Ingerslev · Aalborg University Hospital

Ulla Breth Knudsen

Abstract

Our findings question the use of miRNAs as a reliable biomarker and highlight the need for a critical methodological approach in miRNA studies. Interestingly, tiRNA fragments appear to be overexpressed in conditioned IVF media samples and could potentially be a novel biomarker worthy of investigation.

Topics & Keywords

MicroRNA in disease regulation Reproductive Biology and Fertility Reproductive System and Pregnancy

Publication Details

Published in: Journal of Assisted Reproduction and Genetics

Volume 37, Issue 9, pp. 2199-2209

DOI: 10.1007/s10815-020-01891-7

Field-Weighted Citation Impact: 0.56

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Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid

Authors

Abstract

Topics & Keywords

Publication Details