Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

2020179 citationsReviewdiamond Open Access

Authors

Andrea Cortegiani · Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo

Mariachiara Ippolito · Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo

Massimiliano Greco · Humanitas University

V. Granone · Istituti di Ricovero e Cura a Carattere Scientifico

Alessandro Protti · Istituti di Ricovero e Cura a Carattere Scientifico

Cesare Gregoretti · Fondazione Istituto G. Giglio di Cefalù

Abstract

There is insufficient evidence regarding the clinical efficacy and safety of tocilizumab in patients with COVID-19. Its use should be considered experimental, requiring ethical approval and clinical trial oversight.

Topics & Keywords

COVID-19 Clinical Research Studies Long-Term Effects of COVID-19 COVID-19 Impact on Reproduction

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pulmonology

Volume 27, Issue 1, pp. 52-66

DOI: 10.1016/j.pulmoe.2020.07.003

Field-Weighted Citation Impact: 4.24