Maternal Hypertension-Related Genotypes and Congenital Heart Defects

20206 citationsJournal Articlebronze Open Access

Authors

Yunping Lei · Baylor College of Medicine

Katherine L. Ludorf · The University of Texas Health Science Center at Houston

Xiao Yu · The University of Texas Health Science Center at Houston

Renata H. Benjamin · The University of Texas Health Science Center at Houston

Xue Gu · Baylor College of Medicine

Ying Lin · Baylor College of Medicine

Richard H. Finnell

Abstract

We replicated a previously reported association between rs633185 and conotruncal defects. Although additional hypertension-related SNPs were also associated with congenital heart defects, more work is needed to better understand the relationship between genetic risk for maternal hypertension and congenital heart defects occurrence.

Topics & Keywords

Pregnancy and preeclampsia studies Congenital Heart Disease Studies Birth, Development, and Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Hypertension

Volume 34, Issue 1, pp. 82-91

DOI: 10.1093/ajh/hpaa116

Field-Weighted Citation Impact: 0.49

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