Immunothrombotic Dysregulation in COVID-19 Pneumonia Is Associated With Respiratory Failure and Coagulopathy

2020566 citationsJournal Articlebronze Open Access

Authors

Leo Nicolai · LMU Klinikum

Alexander Leunig · LMU Klinikum

Sophia Brambs · LMU Klinikum

Rainer Kaiser · LMU Klinikum

Tobias Weinberger · LMU Klinikum

Michael Weigand · Ludwig-Maximilians-Universität München

Maximilian Muenchhoff ·

Abstract

Taken together, our data point to immunothrombotic dysregulation as a key marker of disease severity in COVID-19. Further work is necessary to determine the role of immunothrombosis in COVID-19.

Topics & Keywords

COVID-19 Clinical Research Studies Inflammasome and immune disorders Adipokines, Inflammation, and Metabolic Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 142, Issue 12, pp. 1176-1189

DOI: 10.1161/circulationaha.120.048488

Field-Weighted Citation Impact: 12.32