Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

20201,153 citationsJournal Articlegreen Open Access

Authors

Kizzmekia S. Corbett · Norwegian Womens Public Health Association

Barbara J. Flynn · Norwegian Womens Public Health Association

Kathryn E. Foulds · Norwegian Womens Public Health Association

Joseph R. Francica · Norwegian Womens Public Health Association

Seyhan Boyoglu-Barnum · Norwegian Womens Public Health Association

Anne P. Werner · Norwegian Womens Public Health Association

Abstract

Vaccination of nonhuman primates with mRNA-1273 induced robust SARS-CoV-2 neutralizing activity, rapid protection in the upper and lower airways, and no pathologic changes in the lung. (Funded by the National Institutes of Health and others.).

Topics & Keywords

SARS-CoV-2 and COVID-19 Research Animal Virus Infections Studies Viral gastroenteritis research and epidemiology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 383, Issue 16, pp. 1544-1555

DOI: 10.1056/nejmoa2024671

Field-Weighted Citation Impact: 25.37