Association of the RPA3-UMAD1 locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese

202035 citationsReviewhybrid Open Access

Authors

Yuya Shirai · Osaka University

Suguru Honda · Tokyo Women's Medical University

Katsunori Ikari · Tokyo Women's Medical University

Masahiro Kanai · Harvard University

Yoshito Takeda · Osaka University

Yoichiro Kamatani · RIKEN Center for Integrative Medical Sciences

Takayuki Morisaki

Abstract

We revealed one novel genetic association with RA-ILD in Japanese. The RA-ILD risk of the identified variant at <i>RPA3-UMAD1</i> was relatively high in the CT image patterns related to fibrosis. Our study should contribute to elucidation of the complicated aetiology of RA-ILD.

Topics & Keywords

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Inflammasome and immune disorders Eosinophilic Disorders and Syndromes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of the Rheumatic Diseases

Volume 79, Issue 10, pp. 1305-1309

DOI: 10.1136/annrheumdis-2020-217256

Field-Weighted Citation Impact: 2.53