Analyzing and validating the prognostic value and mechanism of colon cancer immune microenvironment

2020100 citationsJournal Articlegold Open Access

Authors

Jinzhong Duanmu · First Affiliated Hospital of Nanchang University

Taiyuan Li · First Affiliated Hospital of Nanchang University

Abstract

We performed a comprehensive evaluation of the immune microenvironment landscape of colon cancer and demonstrated the positive correlation between immunity and TMB. The hub genes and frequently mutated genes were strongly related to immunity and may give suggestion for immunotherapy in the future.

Topics & Keywords

Ferroptosis and cancer prognosis Cancer Immunotherapy and Biomarkers Genetic factors in colorectal cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Translational Medicine

Volume 18, Issue 1, pp. 324-324

DOI: 10.1186/s12967-020-02491-w

Field-Weighted Citation Impact: 10.00