Validation of differentially expressed brain‐enriched microRNAs in the plasma of PD patients

202071 citationsJournal Articlegold Open Access

Authors

Stylianos Ravanidis · Academy of Athens

Anastasia Bougea · National and Kapodistrian University of Athens

Nikolaos Papagiannakis · National and Kapodistrian University of Athens

Christos Koros · National and Kapodistrian University of Athens

Athina Maria Simitsi · National and Kapodistrian University of Athens

Ioanna Pachi · National and Kapodistrian University of Athens

Marianthi Breza

Abstract

We validated a panel of brain-enriched miRNAs that can be used along with other measures for the detection of PD, revealed molecular pathways targeted by these deregulated miRNAs, and identified upstream transcription factors that may be directly implicated in PD pathogenesis.

Topics & Keywords

MicroRNA in disease regulation Extracellular vesicles in disease Circular RNAs in diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Clinical and Translational Neurology

Volume 7, Issue 9, pp. 1594-1607

DOI: 10.1002/acn3.51146

Field-Weighted Citation Impact: 2.55