Circulating Tumor DNA as a Prognostic Biomarker in Localized Non-small Cell Lung Cancer

2020111 citationsJournal Articlegold Open Access

Authors

Muyun Peng · Central South University

Qi Huang · Central South University

Wei Yin · Central South University

Sichuang Tan · Second Xiangya Hospital of Central South University

Chen Chen · Second Xiangya Hospital of Central South University

Wenliang Liu · Second Xiangya Hospital of Central South University

Jingqun Tang

Abstract

Advanced stage and preoperative ctDNA-positive are strong predictors of RFS and OS in localized NSCLC patients undergoing complete resection. Postoperative detection of ctDNA increases chance to detect early relapse, thus can fulfill an important role in stratifying patients for immediate further treatment with adjuvant and neoadjuvant therapy.

Topics & Keywords

Cancer Genomics and Diagnostics Lung Cancer Treatments and Mutations Cholangiocarcinoma and Gallbladder Cancer Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Oncology

Volume 10, pp. 561598-561598

DOI: 10.3389/fonc.2020.561598

Field-Weighted Citation Impact: 7.02