Interleukin-6 and severe COVID-19: a systematic review and meta-analysis

2020103 citationsReview

Authors

Helia Mojtabavi · Universal Scientific Education and Research Network

Amene Saghazadeh · Universal Scientific Education and Research Network

Nima Rezaei · Universal Scientific Education and Research Network

Abstract

Meta-analysis and meta-regression reveal a reliable relationship between IL-6 and COVID-19 severity, independent of age and sex. Future research is, however, required to assess the effect of BMI on the pattern of IL-6 production in patients with COVID-19. Also, there might be confounding factors that influence the relationship between IL-6 and COVID-19 severity and remain as yet unknown.

Topics & Keywords

COVID-19 Clinical Research Studies Long-Term Effects of COVID-19 SARS-CoV-2 and COVID-19 Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: European Cytokine Network

Volume 31, Issue 2, pp. 44-49

DOI: 10.1684/ecn.2020.0448

Field-Weighted Citation Impact: 2.27