Subthalamic Nucleus Deep Brain Stimulation Modulates 2 Distinct Neurocircuits

202094 citationsJournal Articlegreen Open Access

Authors

Lunhao Shen · Harvard University

Changqing Jiang · Zero to Three

Catherine S. Hubbard · Medical University of South Carolina

Jianxun Ren · Harvard University

Changgeng He · Harvard University

Danhong Wang · Harvard University

Louisa Dahmani ·

Abstract

Concurrent DBS-fMRI using 3T revealed 2 distinct circuits that responded differentially to STN-DBS and were related to divergent symptoms, a finding that may provide novel insights into the neural mechanisms underlying DBS. ANN NEUROL 2020;88:1178-1193.

Topics & Keywords

Neurological disorders and treatments Parkinson's Disease Mechanisms and Treatments Genetic Neurodegenerative Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Neurology

Volume 88, Issue 6, pp. 1178-1193

DOI: 10.1002/ana.25906

Field-Weighted Citation Impact: 4.85