Decreased Mortality in Coronavirus Disease 2019 Patients Treated With Tocilizumab: A Rapid Systematic Review and Meta-analysis of Observational Studies

2020123 citationsReviewbronze Open Access

Authors

Jishnu Malgie · Leiden University Medical Center

Bart G. Pijls · Leiden University Medical Center

Abstract

Our results showed that mortality was 12% lower for COVID-19 patients treated with TCZ compared with those not treated with TCZ. The number needed to treat was 11, suggesting that for every 11 (severe) COVID-19 patients treated with TCZ, 1 death is prevented. These results require confirmation by randomized controlled trials.

Topics & Keywords

COVID-19 Clinical Research Studies SARS-CoV-2 and COVID-19 Research Long-Term Effects of COVID-19

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 72, Issue 11, pp. e742-e749

DOI: 10.1093/cid/ciaa1445

Field-Weighted Citation Impact: 2.76