Sensitive Detection of SARS-CoV-2–Specific Antibodies in Dried Blood Spot Samples

202095 citationsJournal Articlediamond Open Access

Authors

Gabriella L. Morley · University of Oxford

Stephen Taylor · University Hospitals Birmingham NHS Foundation Trust

Siân E. Jossi · University Hospitals Birmingham NHS Foundation Trust

Marisol Pérez-Toledo · Save the Children

Sian Faustini · University of Southampton

Edith Marcial‐Juárez · University of Oxford

Adrian Shields

Abstract

Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.

Topics & Keywords

SARS-CoV-2 and COVID-19 Research SARS-CoV-2 detection and testing Biosimilars and Bioanalytical Methods

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Emerging infectious diseases

Volume 26, Issue 12, pp. 2970-2973

DOI: 10.3201/eid2612.203309

Field-Weighted Citation Impact: 1.89