Roles of IFN-γ in tumor progression and regression: a review

20201,178 citationsReviewgold Open Access

Authors

Dragica Jorgovanović · First Affiliated Hospital of Zhengzhou University

Liping Wang · First Affiliated Hospital of Zhengzhou University

Abstract

Significant research efforts are required to decipher IFN-γ-dependent pro- and anti-tumorigenic effects. This review discusses the current knowledge concerning the roles of IFN-γ in the TME as a part of the complex immune response to cancer and highlights the importance of identifying IFN-γ responsive patients to improve their sensitivity to immuno-therapies.

Topics & Keywords

Immune cells in cancer Cancer Immunotherapy and Biomarkers Cancer, Stress, Anesthesia, and Immune Response

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Biomarker Research

Volume 8, Issue 1, pp. 49-49

DOI: 10.1186/s40364-020-00228-x

Field-Weighted Citation Impact: 39.29