Resveratrol mediates mechanical allodynia through modulating inflammatory response via the TREM2-autophagy axis in SNI rat model

202075 citationsJournal Articlegold Open Access

Authors

Yaping Wang · Ministry of Education

Yu Shi · Zhujiang Hospital

Yongquan Huang · Sun Yat-sen University

Wei Liu · Shenzhen University

Guiyuan Cai · Zhujiang Hospital

Shimin Huang · Zhujiang Hospital

Yanyan Zeng · Zhujiang Hospital

Abstract

Taken together, these data reveal that resveratrol relieves neuropathic pain through suppressing microglia-mediated neuroinflammation via regulating the TREM2-autophagy axis in SNI rats.

Topics & Keywords

Pain Mechanisms and Treatments Neuroinflammation and Neurodegeneration Mechanisms Pharmacological Effects of Natural Compounds

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Neuroinflammation

Volume 17, Issue 1, pp. 311-311

DOI: 10.1186/s12974-020-01991-2

Field-Weighted Citation Impact: 4.82