Peripheral blood levels of brain-derived neurotrophic factor in patients with post-traumatic stress disorder (PTSD): A systematic review and meta-analysis

202085 citationsReviewgold Open Access

Authors

Helia Mojtabavi · Tehran University of Medical Sciences

Amene Saghazadeh · Children's Medical Center

Leigh L. van den Heuvel · Stellenbosch University

Joana Bücker · Universidade Federal do Rio Grande do Sul

Abstract

PTSD patients had increased serum BDNF levels compared to healthy controls. Our finding of higher BDNF levels in patients with PTSD supports the notion that PTSD is a neuroplastic disorder.

Topics & Keywords

Nerve injury and regeneration Posttraumatic Stress Disorder Research Stress Responses and Cortisol

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 15, Issue 11, pp. e0241928-e0241928

DOI: 10.1371/journal.pone.0241928

Field-Weighted Citation Impact: 4.99