Boron neutron capture therapy using cyclotron-based epithermal neutron source and borofalan (10B) for recurrent or locally advanced head and neck cancer (JHN002): An open-label phase II trial

2020235 citationsJournal Articlehybrid Open Access

Authors

Katsumi Hirose · Hirosaki University

Akiyoshi Konno · Southern Tohoku General Hospital

Junichi Hiratsuka · Kawasaki Medical School

Seiichi Yoshimoto · Tokyo National Hospital

Takahiro Katō · Fukushima Medical University

Koji Ono · Osaka Medical and Pharmaceutical University

Naoki Otsuki

Abstract

These data suggest that BNCT using C-BENS with borofalan (<sup>10</sup>B) is a promising treatment option for patients with R-SCC or R/LA-nSCC of the head and neck.

Topics & Keywords

Boron Compounds in Chemistry Medical Imaging Techniques and Applications Radiopharmaceutical Chemistry and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Radiotherapy and Oncology

Volume 155, pp. 182-187

DOI: 10.1016/j.radonc.2020.11.001

Field-Weighted Citation Impact: 10.95