Characterizing the Genetic Architecture of Parkinson's Disease in Latinos

2021105 citationsJournal Articlegreen Open Access

Authors

Douglas P. Loesch · Human Genome Sciences (United States)

Andréa R. V. R. Horimoto · University of Washington

Karl Heilbron · 23andMe (United States)

Elif Irem Sarihan · Cleveland Clinic Lerner College of Medicine

Miguel Inca‐Martinez · Cleveland Clinic Lerner College of Medicine

Emily Mason · Cleveland Clinic Lerner College of Medicine

Mario Cornejo‐Olivas

Abstract

This study demonstrated the importance of the SNCA locus for the etiology of PD in Latinos. By leveraging the demographic history of our cohort via admixture mapping, we identified two potential PD risk loci that merit further study. ANN NEUROL 2021;90:353-365.

Topics & Keywords

Genetic Associations and Epidemiology CRISPR and Genetic Engineering Parkinson's Disease Mechanisms and Treatments

Publication Details

Published in: Annals of Neurology

Volume 90, Issue 3, pp. 353-365

DOI: 10.1002/ana.26153

Field-Weighted Citation Impact: 13.16

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Characterizing the Genetic Architecture of Parkinson's Disease in Latinos

Authors

Abstract

Topics & Keywords

Publication Details