RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer

2020125 citationsJournal Articlehybrid Open Access

Authors

Lei Sun · Sun Yat-sen University

Arabella Wan · Sun Yat-sen University

Zhuolong Zhou · Indiana University School of Medicine

Dongshi Chen · University of Pittsburgh

Heng Liang · Sun Yat-sen University

Chuwei Liu · Sun Yat-sen University

Shijia Yan ·

Abstract

Collectively, our results reveal a critical metabolism-centric role of RALY in tumour progression, which may lead to cancer therapeutics targeting RALY for treating CRC.

Topics & Keywords

RNA modifications and cancer RNA Research and Splicing Cancer-related molecular mechanisms research

Publication Details

Published in: Gut

Volume 70, Issue 9, pp. 1698-1712

DOI: 10.1136/gutjnl-2020-320652

Field-Weighted Citation Impact: 7.18

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RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer

Authors

Abstract

Topics & Keywords

Publication Details