Markers of endothelial and epithelial pulmonary injury in mechanically ventilated COVID-19 ICU patients

2021153 citationsJournal Articlegold Open Access

Authors

Savino Spadaro · University of Ferrara

Alberto Fogagnolo · University of Ferrara

Gianluca Campo · Maria Cecilia Hospital

Ottavio Zucchetti · Maria Cecilia Hospital

Marco Verri · University of Ferrara

Irene Ottaviani · University of Ferrara

Tanushree Tunstall ·

Abstract

COVID-19 ARDS is characterized by an early pulmonary endothelial injury, as detected by Ang-2 and ICAM-1. COVID-19 ARDS and classical ARDS exhibited a different expression of biomarkers, suggesting different pathological pathways. Trial registration NCT04343053 , Date of registration: April 13, 2020.

Topics & Keywords

Respiratory Support and Mechanisms Sepsis Diagnosis and Treatment COVID-19 Clinical Research Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Critical Care

Volume 25, Issue 1, pp. 74-74

DOI: 10.1186/s13054-021-03499-4

Field-Weighted Citation Impact: 19.23