ZNF703 promotes tumor progression in ovarian cancer by interacting with HE4 and epigenetically regulating PEA15

202064 citationsJournal Articlegold Open Access

Authors

Shuang Wang · China Medical University

Caixia Wang · Sichuan University

Yuexin Hu · China Medical University

Xiao Li · China Medical University

Shan Jin · Liaoning Cancer Hospital & Institute

Ouxuan Liu · China Medical University

Rui Gou ·

Abstract

The results showed that ZNF703 as an oncogene played an important role in the epigenetic modification of ovarian cancer proliferation, and suggested that ZNF703 as a transcription factor may become a prognostic factor and a potential therapeutic target for ovarian cancer.

Topics & Keywords

RNA modifications and cancer Ovarian cancer diagnosis and treatment Epigenetics and DNA Methylation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Experimental & Clinical Cancer Research

Volume 39, Issue 1, pp. 264-264

DOI: 10.1186/s13046-020-01770-0

Field-Weighted Citation Impact: 1.50