Immunohistochemical Detection of Synuclein Pathology in Skin in Idiopathic Rapid Eye Movement Sleep Behavior Disorder and Parkinsonism

202058 citationsJournal Articlegreen Open Access

Authors

Ahmed Al‐Qassabi · Montreal General Hospital

Tsu‐Shuen Tsao · Roche (United States)

Adriana Racolta · Roche (United States)

Thomas Kremer · Roche (Switzerland)

Marta Cañamero · Roche (Switzerland)

Anton Belousov · Roche (Switzerland)

Madison A. Santana ·

Abstract

Even with a single 3-mm punch biopsy, there is considerable promise for using pathological alpha-synuclein deposition in skin to diagnose both clinical and prodromal PD. © 2020 International Parkinson and Movement Disorder Society.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments Neurological disorders and treatments Botulinum Toxin and Related Neurological Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Movement Disorders

Volume 36, Issue 4, pp. 895-904

DOI: 10.1002/mds.28399

Field-Weighted Citation Impact: 2.96