Plasma Amyloid-β Oligomerization Tendency Predicts Amyloid PET Positivity

202119 citationsJournal Articlegold Open Access

Authors

Jung‐Min Pyun · Eulji University

Ji Sun Ryu · PeopleBio (South Korea)

Ryan Lee · PeopleBio (South Korea)

Kyu-Hwan Shim · Veterans Health Service Medical Center

Young Chul Youn · Chung-Ang University

Nayoung Ryoo · Seoul National University Bundang Hospital

Sang‐Won Han ·

Abstract

The Aβ oligomerization tendency in plasma could predict amyloid PET positivity with high performance, and, when it is combined with age, MMSE score, and APOE ε4 status, predictability was improved substantially. This suggests the potential of MDS-OAβ as a useful initial stage test in the clinical and research fields of AD.

Topics & Keywords

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Functional Brain Connectivity Studies

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Clinical Interventions in Aging

Volume Volume 16, pp. 749-755

DOI: 10.2147/cia.s312473

Field-Weighted Citation Impact: 1.98