Peptides as a platform for targeted therapeutics for cancer: peptide–drug conjugates (PDCs)

2020375 citationsReviewhybrid Open Access

Authors

Bethany Cooper · University of Cambridge

Daniel H. O’Donovan · AstraZeneca (United Kingdom)

Maria Ölwegård Halvarsson · AstraZeneca (Brazil)

David R. Spring · University of Cambridge

Abstract

A tutorial review showcasing how peptide–drug conjugates can offer the versatility needed for a successful drug discovery approach, their problems and future opportunities.

Topics & Keywords

Chemical Synthesis and Analysis Click Chemistry and Applications Peptidase Inhibition and Analysis

Publication Details

Published in: Chemical Society Reviews

Volume 50, Issue 3, pp. 1480-1494

DOI: 10.1039/d0cs00556h

Field-Weighted Citation Impact: 14.13

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Peptides as a platform for targeted therapeutics for cancer: peptide–drug conjugates (PDCs)

Authors

Abstract

Topics & Keywords

Publication Details