A pilot clinical trial with losartan in Myhre syndrome

202018 citationsJournal Articlehybrid Open Access

Authors

Gerarda Cappuccio · Federico II University Hospital

Martina Caiazza · University of Campania "Luigi Vanvitelli"

Alessandro Roca · Federico II University Hospital

Daniela Melis · Federico II University Hospital

Antonella Iuliano · Telethon Institute Of Genetics And Medicine

Gábor Mátyás · Foundation for People with Rare Diseases

Marta Rubino

Abstract

Although further long-term controlled clinical trials with a larger number of affected individuals are needed, the present study suggests that losartan might improve skin, joint and heart abnormalities of MS.

Topics & Keywords

Connective tissue disorders research Protein Tyrosine Phosphatases Congenital heart defects research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Medical Genetics Part A

Volume 185, Issue 3, pp. 702-709

DOI: 10.1002/ajmg.a.62019

Field-Weighted Citation Impact: 1.26