Anti-EGFR-mAb and 5-Fluorouracil Conjugated Polymeric Nanoparticles for Colorectal Cancer

202021 citationsJournal Article

Authors

Sankha Bhattacharya · Friendship College

Abstract

From the outcomes of various experiments, it was concluded that Anti-EGFR-5-FUPLGA- PEG-NP has biphasic drug release kinetics, higher cellular uptake and higher cytotoxicity. Therefore, anti-EGFR-5-FU-PLGA-PEG-NP holds excellent potential for drug delivery to EGFR positive colorectal cancer cells.

Topics & Keywords

Nanoparticle-Based Drug Delivery Cancer Treatment and Pharmacology Colorectal Cancer Treatments and Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Recent Patents on Anti-Cancer Drug Discovery

Volume 16, Issue 1, pp. 84-100

DOI: 10.2174/1574892815666201221121859

Field-Weighted Citation Impact: 1.11