Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19

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Authors

Michael J. Joyner · Johns Hopkins University

Rickey E. Carter · Johns Hopkins University

Jonathon W. Senefeld · Johns Hopkins University

Stephen A. Klassen · Johns Hopkins University

John R. Mills · Johns Hopkins University

Patrick W. Johnson · Johns Hopkins University

Elitza S. Theel

Abstract

Among patients hospitalized with Covid-19 who were not receiving mechanical ventilation, transfusion of plasma with higher anti-SARS-CoV-2 IgG antibody levels was associated with a lower risk of death than transfusion of plasma with lower antibody levels. (Funded by the Department of Health and Human Services and others; ClinicalTrials.gov number, NCT04338360.).

Topics & Keywords

COVID-19 Clinical Research Studies SARS-CoV-2 and COVID-19 Research Long-Term Effects of COVID-19

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 384, Issue 11, pp. 1015-1027

DOI: 10.1056/nejmoa2031893

Field-Weighted Citation Impact: 34.27