Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments

2021459 citationsReviewgold Open Access

Authors

Xiaoxu Wei · Central South University

Yunhua Chen · Central South University

Xianjie Jiang · Central South University

Peng Miao · Central South University

Yiduo Liu · Central South University

Yongzhen Mo · Central South University

Daixi Ren ·

Abstract

Overall, the use of VM inhibitors in combination with conventional anti-angiogenesis treatments is a promising strategy for improving the effectiveness of targeted angiogenesis treatments; further, considering the importance of hypoxia in tumor invasion and metastasis, drugs targeting the hypoxia signaling pathway seem to achieve good results.

Topics & Keywords

Cancer, Hypoxia, and Metabolism Angiogenesis and VEGF in Cancer High Altitude and Hypoxia

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 20, Issue 1, pp. 7-7

DOI: 10.1186/s12943-020-01288-1

Field-Weighted Citation Impact: 31.06