Magnetic resonance thermometry using a Gd<sup>III</sup>-based contrast agent

20215 citationsJournal Articlegreen Open Access

Authors

S. A. Amali S. Subasinghe · Wayne State University

Jonathan Romero · Baylor College of Medicine

Cassandra L. Ward · Wayne State University

Matthew D. Bailey · Wayne State University

Donna R. Zehner · Baylor College of Medicine

Prakrut J. Mehta · Baylor College of Medicine

Fabio Carniato

Abstract

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluoromethyl groups that can be chemically controlled.

Topics & Keywords

Lanthanide and Transition Metal Complexes Advanced MRI Techniques and Applications Luminescence Properties of Advanced Materials

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Chemical Communications

Volume 57, Issue 14, pp. 1770-1773

DOI: 10.1039/d0cc06400a

Field-Weighted Citation Impact: 0.32