Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT

202118 citationsJournal Articlehybrid Open Access

Authors

Marie‐Pierre Dubé

Marc‐André Legault

Audrey Lemaçon

Louis‐Philippe Lemieux Perreault

Wolfgang Köenig · German Centre for Cardiovascular Research

Abstract

We found 2 genomic regions associated with gastrointestinal events in patients treated with colchicine. Those findings will benefit from replication to confirm that some patients may have genetic predispositions to lower tolerability of treatment with colchicine.

Topics & Keywords

Inflammasome and immune disorders Lipoproteins and Cardiovascular Health Atherosclerosis and Cardiovascular Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Genomic and Precision Medicine

Volume 14, Issue 2, pp. e003183-e003183

DOI: 10.1161/circgen.120.003183

Field-Weighted Citation Impact: 1.05