Cordycepin Ameliorates Nonalcoholic Steatohepatitis by Activation of the AMP‐Activated Protein Kinase Signaling Pathway

2021166 citationsJournal Articlehybrid Open Access

Authors

Tian Lan · Guangzhou University of Chinese Medicine

Yu Yang · Guangzhou University of Chinese Medicine

Jing Zhang · Guangzhou University of Chinese Medicine

Haonan Li · Guangzhou University of Chinese Medicine

Qiqing Weng · Guangzhou University of Chinese Medicine

Shuo Jiang · Guangzhou University of Chinese Medicine

Song Tian

Abstract

Cordycepin exerts significant protective effects against hepatic steatosis, inflammation, liver injury, and fibrosis in mice under metabolic stress through activation of the AMPK signaling pathway. Cordycepin might be an AMPK activator that can be used for the treatment of NASH.

Topics & Keywords

Metabolism, Diabetes, and Cancer Liver Disease Diagnosis and Treatment Pancreatic function and diabetes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hepatology

Volume 74, Issue 2, pp. 686-703

DOI: 10.1002/hep.31749

Field-Weighted Citation Impact: 8.13