NADPH and Mito-Apocynin Treatment Protects Against KA-Induced Excitotoxic Injury Through Autophagy Pathway

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Authors

Na Liu · Soochow University

Miaomiao Lin · Soochow University

Sisi Huang · Soochow University

Ziqi Liu · Soochow University

Junchao Wu · Soochow University

Zhong‐Qin Liang · Soochow University

Zheng‐Hong Qin · Soochow University

Abstract

In summary, combined administration of NADPH and NOX inhibitors offers better neuroprotection by reducing NADPH as a NOX substrate to generate ROS. The combined use of NADPH and Mito-apocynin can better restore neurons and mitochondrial function through autophagy pathway.

Topics & Keywords

Neuroinflammation and Neurodegeneration Mechanisms Autophagy in Disease and Therapy Mitochondrial Function and Pathology

Publication Details

Published in: Frontiers in Cell and Developmental Biology

Volume 9, pp. 612554-612554

DOI: 10.3389/fcell.2021.612554

Field-Weighted Citation Impact: 1.57

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NADPH and Mito-Apocynin Treatment Protects Against KA-Induced Excitotoxic Injury Through Autophagy Pathway

Authors

Abstract

Topics & Keywords

Publication Details