ZIKA Virus Neutralizing Antibody Kinetics in Antenatally Exposed Infants

20218 citationsJournal Articlegreen Open Access

Authors

Otávio de Melo Espíndola · Fundação Oswaldo Cruz

Thomas Jaenisch · Center for Global Health

Karin Nielsen‐Saines · University of California, Los Angeles

Raquel de Vasconcellos Carvalhães de Oliveira · Instituto Evandro Chagas

Boris Pastorino · Aix-Marseille Université

Zilton Vasconcelos · Fundação Oswaldo Cruz

Claudia Raja Gabaglia

Abstract

Infants with antenatal ZIKV exposure do not develop ZIKV nAb despite an early IgM response. Therefore, ZIKV VNT in children is not useful for diagnosis of congenital infection. In light of these findings, it remains to be determined if children infected in utero are potentially susceptible to reinfection.

Topics & Keywords

Mosquito-borne diseases and control Virology and Viral Diseases Viral Infections and Vectors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Infectious Diseases

Volume 224, Issue 6, pp. 1060-1068

DOI: 10.1093/infdis/jiab054

Field-Weighted Citation Impact: 0.77