Genetic Effects on Transcriptome Profiles in Colon Epithelium Provide Functional Insights for Genetic Risk Loci

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Authors

Virginia Díez‐Obrero · Institut d'Investigació Biomédica de Bellvitge

Christopher H. Dampier · University of Virginia

Ferrán Moratalla-Navarro · Institut Català d'Oncologia

Matthew A.M. Devall · University of Virginia Health System

Sarah J. Plummer · University of Virginia Health System

Anna Díez-Villanueva · Institut d'Investigació Biomédica de Bellvitge

Ulrike Peters

Abstract

We provide a large characterization of gene expression and splicing across colon subsites. Our findings provide greater etiologic insight into complex traits and diseases influenced by transcriptomic changes in colon tissue.

Topics & Keywords

Genetic factors in colorectal cancer Helicobacter pylori-related gastroenterology studies Colorectal Cancer Screening and Detection

Publication Details

Published in: Cellular and Molecular Gastroenterology and Hepatology

Volume 12, Issue 1, pp. 181-197

DOI: 10.1016/j.jcmgh.2021.02.003

Field-Weighted Citation Impact: 5.16

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Genetic Effects on Transcriptome Profiles in Colon Epithelium Provide Functional Insights for Genetic Risk Loci

Authors

Abstract

Topics & Keywords

Publication Details