FAM83H‐AS1 is a noncoding oncogenic driver and therapeutic target of lung adenocarcinoma

202116 citationsJournal Articlegold Open Access

Authors

Siwei Wang · Jiangsu Cancer Hospital

Chencheng Han · Jiangsu Cancer Hospital

Tongyan Liu · Jiangsu Cancer Hospital

Zhifei Ma · Jiangsu Cancer Hospital

Mantang Qiu · Peking University

Jie Wang · BioBank Japan

Qingjun You · Jiangnan University

Abstract

Our work demonstrates that FAM83H-AS1 is a noncoding oncogenic driver that inhibits LUAD apoptosis via the FAM83H-AS1-HNRNPK-RAB8B/RAB14 axis, which highlights the importance and potential roles that FAM83H-AS1 may serve as a novel therapeutic target for LUAD.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical and Translational Medicine

Volume 11, Issue 2, pp. e316-e316

DOI: 10.1002/ctm2.316

Field-Weighted Citation Impact: 1.40