Serum Uric Acid in LRRK2 Related Parkinson’s Disease: Longitudinal Data from the PPMI Study

20217 citationsJournal Article

Authors

Anastasia Bougea · Eginition Hospital

Christos Koros · University General Hospital Attikon

Nikolaos Papagiannakis · National and Kapodistrian University of Athens

Athina‐Maria Simitsi · National and Kapodistrian University of Athens

Andreas Prentakis · University General Hospital Attikon

Dimitra Papadimitriou · Henry Dunant Hospital

Ioanna Pachi

Abstract

LRRK2 + PD group had significantly lower uric acid concentrations compared to HC after adjusting for age, sex and baseline BMI up to 5 years follow-up. There were no significant associations between uric acid levels and indices of disease severity. These findings identify serum uric acid as a marker linked to LRRK2 + PD.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Parkinson s Disease

Volume 11, Issue 2, pp. 633-640

DOI: 10.3233/jpd-202337

Field-Weighted Citation Impact: 0.43

Command Palette