Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction

2021172 citationsJournal Articlegreen Open Access

Authors

Fernando Riveros-Mckay · S.P.E.C.I.E.S.

Michael E. Weale · S.P.E.C.I.E.S.

Rachel Moore · S.P.E.C.I.E.S.

Saskia Selzam · S.P.E.C.I.E.S.

Eva Krapohl · Norwegian Womens Public Health Association

R. Michael Sivley · S.P.E.C.I.E.S.

William A. Tarran ·

Abstract

An IRT that includes polygenic risk outperforms current risk stratification tools and offers greater opportunity for early interventions. Given the plummeting costs of genetic tests, future iterations of CAD risk tools would be enhanced with the addition of a person's polygenic risk.

Topics & Keywords

Genetic Associations and Epidemiology Lipoproteins and Cardiovascular Health Cardiovascular Function and Risk Factors

Publication Details

Published in: Circulation Genomic and Precision Medicine

Volume 14, Issue 2, pp. e003304-e003304

DOI: 10.1161/circgen.120.003304

Field-Weighted Citation Impact: 23.20

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Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction

Authors

Abstract

Topics & Keywords

Publication Details