Interferon-gamma release assay levels and risk of progression to active tuberculosis: a systematic review and dose-response meta-regression analysis

202149 citationsReviewgold Open Access

Authors

Jorge R Ledesma · Institute for Health Metrics and Evaluation

Jianing Ma · University of Washington

Peng Zheng · University of Washington

Jennifer M. Ross · Seattle Pacific University

Theo Vos · University of Washington

Hmwe Hmwe Kyu · University of Washington

Abstract

The current practice of dichotomizing IGRA test results simplifies the TB infection disease continuum. Evaluating IGRA test results over a continuous scale could enable the identification of individuals at greatest risk of progression to active TB.

Topics & Keywords

Tuberculosis Research and Epidemiology Infectious Diseases and Tuberculosis Pneumonia and Respiratory Infections

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Infectious Diseases

Volume 21, Issue 1, pp. 467-467

DOI: 10.1186/s12879-021-06141-4

Field-Weighted Citation Impact: 1.95