Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-α/NF-κB/caspase-3 signaling in type 2 diabetes rats

202173 citationsJournal Article

Authors

Xiaohong Chen · Shaanxi Provincial Hospital of Traditional Chinese Medicine

Ademola C. Famurewa · Alex Ekwueme Federal University, Ndufu-Alike

Oladipupo Odunayo Olatunde · Prince of Songkla University

Opeyemi Joshua Olatunji · Prince of Songkla University

Abstract

The results suggested that hyperoside prevents DM-induced cognitive dysfunction, neuroinflammation and oxidative stress via antioxidant, anti-inflammatory and antiapoptotic mechanisms in rats.

Topics & Keywords

Neuroinflammation and Neurodegeneration Mechanisms Alzheimer's disease research and treatments Natural Antidiabetic Agents Studies

Publication Details

Published in: Nutritional Neuroscience

Volume 25, Issue 8, pp. 1774-1784

DOI: 10.1080/1028415x.2021.1901047

Field-Weighted Citation Impact: 5.07

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Hyperoside attenuates neuroinflammation, cognitive impairment and oxidative stress via suppressing TNF-α/NF-κB/caspase-3 signaling in type 2 diabetes rats

Authors

Abstract

Topics & Keywords

Publication Details