Eosinophil ETosis–Mediated Release of Galectin‐10 in Eosinophilic Granulomatosis With Polyangiitis

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Authors

Mineyo Fukuchi · Akita University

Yosuke Kamide · National Sagamihara Hospital

Shigeharu Ueki · Akita University

Yui Miyabe · Akita University

Yasunori Konno · Akita University

Nobuyuki Oka · Kyoto City Hospital

Hiroki Takeuchi ·

Abstract

Eosinophils infiltrating diseased tissues in EGPA undergo EETosis. Considering the exclusive expression and large pool of cytoplasmic galectin-10 in eosinophils, elevated serum galectin-10 levels in patients with EGPA might reflect the systemic occurrence of cytolytic EETosis.

Topics & Keywords

Eosinophilic Disorders and Syndromes Eosinophilic Esophagitis Vasculitis and related conditions

Publication Details

Published in: Arthritis & Rheumatology

Volume 73, Issue 9, pp. 1683-1693

DOI: 10.1002/art.41727

Field-Weighted Citation Impact: 10.21

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Eosinophil ETosis–Mediated Release of Galectin‐10 in Eosinophilic Granulomatosis With Polyangiitis

Authors

Abstract

Topics & Keywords

Publication Details