EpCam is required for maintaining the integrity of the biliary epithelium

20215 citationsJournal Article

Authors

Yougen Zhan · Icahn School of Medicine at Mount Sinai

Stephen C. Ward · Icahn School of Medicine at Mount Sinai

Maria Isabel Fiel · Icahn School of Medicine at Mount Sinai

Julie Teruya‐Feldstein · Icahn School of Medicine at Mount Sinai

Eileen McKay · Baylor College of Medicine

Fumiko Dekio · Icahn School of Medicine at Mount Sinai

Abstract

Our findings show that TE is associated with disrupted polarity of cholangiocyte and ductopenia. We demonstrate for the first time a role of EpCam in the maintenance of integrity of biliary epithelium. We also provided evidence for a disrupted development of hepatic reparative cells.

Topics & Keywords

Clinical Nutrition and Gastroenterology Pediatric Hepatobiliary Diseases and Treatments Digestive system and related health

Publication Details

Published in: Liver International

Volume 41, Issue 9, pp. 2132-2138

DOI: 10.1111/liv.14891

Field-Weighted Citation Impact: 0.48

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EpCam is required for maintaining the integrity of the biliary epithelium

Authors

Abstract

Topics & Keywords

Publication Details