Malignant peripheral nerve sheath tumors. A clinicopathologic study of 28 cases

1993340 citationsJournal Article

Authors

John E. Wanebo · Naval Medical Research Command

Jacek M. Malik · Neurological Surgery

Scott R. VandenBerg · Brown University

Harold J. Wanebo · Roger Williams Medical Center

Naomi Driesen · Neurological Surgery

John A. Persing · Yale University

Abstract

The authors recommended that patients with NF-1 be followed closely for MPNST development. For most cases, treatment should include aggressive surgery with wide surgical margins combined with adjuvant radiation therapy. Chemotherapy may have a role for treatment failures.

Topics & Keywords

Neurofibromatosis and Schwannoma Cases Soft tissue tumors and treatment Spinal Hematomas and Complications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer

Volume 71, Issue 4, pp. 1247-1253

DOI: 10.1002/1097-0142(19930215)71:4<1247::aid-cncr2820710413>3.0.co;2-s

Field-Weighted Citation Impact: 3.81