Sex differences in soluble prorenin receptor in patients with type 2 diabetes

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Authors

Bruna Visniauskas · Tulane University

Danielle Yuri Arita · Tulane University

C Rosales · Tulane University

Mohammed A. Feroz · Tulane University

Christina Luffman · Tulane University

Michael J. Accavitti · Tulane University

Gabrielle Dawkins ·

Abstract

In patients with type 2 diabetes, sPRR contributes to RAS stimulation in a sex-dependent fashion. In diabetic women, increased plasma sPRR parallels the activation of systemic RAS; while in diabetic men, decreased sPRR in urine matches intrarenal RAS stimulation. sPRR might be a potential indicator of intrarenal RAS activation and renal dysfunction in men and women with type 2 diabetes.

Topics & Keywords

Renin-Angiotensin System Studies Hormonal Regulation and Hypertension Blood Pressure and Hypertension Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Biology of Sex Differences

Volume 12, Issue 1, pp. 33-33

DOI: 10.1186/s13293-021-00374-3

Field-Weighted Citation Impact: 1.88